1 Blood Oxygen Binding in Hypoxaemic Calves
Anne Drescher edited this page 2025-09-29 04:32:26 +08:00
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Blood oxygen transport and tissue oxygenation were studied in 28 calves from the Belgian White and Blue breed (20 healthy and eight hypoxaemic ones). Hypoxaemic calves had been selected in keeping with their excessive respiratory frequency and to their low partial oxygen strain (PaO2) in the arterial blood. Venous and arterial blood samples have been collected, and 2,3-diphosphoglycerate, adenosine triphosphate, chloride, inorganic phosphate and hemoglobin concentrations, BloodVitals SPO2 and pH, PCO, and PO2 have been determined. An oxygen equilibrium curve (OEC) was measured in customary conditions, for each animal. The arterial and venous OEC were calculated, taking body temperature, pH and PCO2 values in arterial and venous blood into account. The oxygen change fraction (OEF%), corresponding to the diploma of blood desaturation between the arterial and the venous compartments, and the quantity of oxygen released on the tissue degree by a hundred mL of blood (OEF Vol%) were calculated from the arterial and venous OEC mixed with the PO2 and hemoglobin focus. In hypoxaemic calves investigated on this study, the hemoglobin oxygen affinity, measured below customary circumstances, was not modified. Quite the opposite, in vivo acidosis and hypercapnia induced a lower within the hemoglobin oxygen affinity in arterial blood, BloodVitals SPO2 which combined to the decrease in PaO2 led to a decreased hemoglobin saturation diploma within the arterial compartment. However, this did not impair the oxygen alternate fraction (OEF%), for the reason that hemoglobin saturation degree in venous blood was also diminished.


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